The FMVs (videos) won't play in fullscreen mode. Workarounds:

1. You can play in windowed mode.
2. You can disable FMVs in the config.
3. You can enable "desktop emulation" in wineconfig. You can open wineconfig with the following command:

protontricks 225000

I've emulated the desktop with the resolution 1024*720, and set the in-game resolution to 1920*1080 in fullscreen mode. The game opened in fullscreen, and the FMVs were played in 640*480 windows.