Without the No Esync launch flag, cinematics (such as the main menu background video, pre-mission briefings, and in-mission communications) cause the game to lag horribly. With it enabled, the game seems to run flawlessly.

Changing resolutions causes the visual part of the game to appear in a different place than it should. For me, it went down and to the right. The interactive elements (the place your mouse needs to be to activate them, not the graphics of the buttons) are still where they should be, so putting my mouse in the middle of my monitor still activates the buttons as if they were still there.