Chose Windowed (vitual desktop) in Lutris, since the game would go black in a corner if you pressed the Windows key for example, and couldn't be opend again without windowed mode.

Fixed it with Windowed mode

Keyboard stopped working at some point, no input was detected ingame anymore, before it worked. Linux still detected input.

Autosave couln't be loaded, manual save games seem to work. Once a manual save wasn't saved, however it's possible that i pressed cancel unawarely, since the switched around button positioning compared to any other game.