I had an issue with frame generation not been available in game. To fix I had to create the REG_DWORD HKEY_LOCAL_MACHINE\System\CurrentControlSet\Control\GraphicsDrivers\HwSchMode with value 2 using the regedit which I opened with the following command:

WINEPREFIX=$HOME/.steam/steam/steamapps/compatdata/2358720/pfx $HOME/.steam/steam/steamapps/common/Proton\ Hotfix/files/bin-wow64/wine regedit