

install vcrun6
Game uses Direct3D8 and will fall back to wined3d - and the game will not mind running in excess of 400+fps when running uncapped, resulting in noticeably more GPU usage than should be necessary. Overwriting/deleting the Steam distribution's preset D3D dlls and setting up a new dgVoodoo2 config (while making a d3d8
Wine dll override) will allow using DXVK, reduce overall overhead, as well as override the game's broken MSAA.
Launcher will not display the .mpg video logos properly, renders black (but can be clicked through to dismiss*)
I could admittedly not get the game to work optimally in Steam: Proton Experimental shows testbars with any video, and ProtonGE shows black on .mpg videos on my setup. But because the game is distributed DRM-free, running through Lutris with a normal Wine prefix (following Winetricks instructions) is totally viable.
The launcher will not launch correctly if the {GAME}\shellmedia\majesco.mpg
file is left as-is. (Re)moving it will display an error message, but dismissing it and clicking the brief black window will allow the Drake shell to load. Resolutions are pre-set, settings need to be re-toggled every time, and the Anti-aliasing option doesn't even work; so just set the highest 32-bit resolution of 1600x1200, use the high pre-set, and disable AA (and use a fresh dgVoodoo2 instance for desired AA instead). After launching, the idol video logo will also display nothing with audio, but can likewise be safely clicked through--and the game itself will load and play perfectly fine.
If the mouse is more sensitive when moving up than down, that's a vanilla bug. If it doesn't seem to save at first, this is also a vanilla bug; delete the version\savegames\Drake
file and try again until it works. If the sound seems too loud at points (virtually no sound ever 'fades' or accounts for distance), that is a Wine bug - but for some reason, the game supports DirectSound3D and can be made to work under Wine (with a dsound
dll override).
Drake of the 99 Dragons does work, through some trials and tribulations.
But, like the title suggests... why would you want it to, is the question.
Launcher does not work, cutscene videos require Proton-GE, and default settings leave the game at a low resolution.
The launcher does not work, which means you cannot change any graphical options on Linux; stuck with defaults
The game's launcher does not properly work on Proton and since there's no launch option to skip it (as far as I'm aware), you have to go to the game's files and rename "Drake.exe" to "drakeshell.exe" (either removing or renaming the actual drakeshell.exe).
You also need to use Proton-GE or another method of getting Media Foundation working so that cutscene videos are playable, otherwise they're stuck showing a color test screen until you skip it.
The game is playable after doing all of this, but you're stuck with whatever default video settings the game uses on PC. There might be some way of copying over a config file from Windows to fix this, but it's not something I've tested (or care really much to try and figure out for this game).

The launcher does not run at all, when using the main game executable however, the game does launch, but later on closes itself.