As of Proon 7.0-1, I can at least get to the title screen and interact with all the menus...except for starting a new game. In prior versions of Proton, the game would immediately crash for me as soon as I finished or quit out of the opening cinematic. Now, upon starting a new game and picking a faction, the screen goes black and the cursor disappears. No error message is shown and it is up to you how long you want to stare into the void.

The title screen has CPU-bound animations that look super funny on modern hardware, but that's not a Proton issue. I've defintiely seen that happen running this game on anything other than the Pentium 4 I first played this game on.