With the current v1.2 of the game, I did once encounter an issue with the "hot spot" of the pointer/center being shifted (so you have to click slightly off center to interact with any objects on the screen).

I have seen this exact same problem occur before with some other Unity engine games (on Windows too), I believe this is a bug that can occur on non 16:9 aspect ratio resolutions. Setting a 16:9 resolution from my experience solves it, on games that don't have resolution options (like this game) it can be done by setting a Steam launch command for example "-screen-fullscreen 1 -screen-width 1920 -screen-height 1080"