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Could not acquire information for App ID: . This can happen if a game was removed from the store.No issues
Intro video does not play, press Esc to skip.
If you have friends to play with, this is probably a good party game.
Game works very will without any glitchses. No adjustments needed.
Seems to work well
It works perfectly fine. Just install and play. No issues.

Some missing video; no impact to gameplay
Some splash videos don't play, and the animated main menu background is missing.
The game works for me with Proton 5.13-1 (as it did with Proton 5.0-9), the only apparent issues being that some of the initial splash videos don't play (leaving only a black screen for several seconds before The Eccentric Ape's logo is shown) and that the animated background of the main menu doesn't work (so the background is just black instead). During gameplay, everything works as expected.

5.9-GE-5-ST GloriousEggroll
https://github.com/GloriousEggroll/proton-ge-custom/releases/tag/5.9-GE-8-ST
Audio stuttering at the initial SEGA logo, and a very brief but irritating buzz noise at the start of the Relic Entertainment splash video.
When I ran the game with Proton 5.0-9, it was perfectly playable, but some of the initial splash videos would not play (leaving only a black screen for several seconds before The Eccentric Ape's logo was shown) and the animated background of the main menu did not work (so the background was just black instead). With Proton 5.9-GE-8-ST, the splash videos play (but with some audio glitches) and the animated main menu background is restored.
Works out of the box. A little bit heavy, so you may need to reduce the settings to avoid slowdowns.
Had to reduce graphical quality a bit, otherwise it will run a little slow.